Adıyaman Üniversitesi Kurumsal Arşivi

The relationship between coronary artery disease and SIRT1 protein

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dc.contributor.author Aşkın, Lütfü
dc.contributor.author Tibilli, Hakan
dc.contributor.author Tanriverdi, Özgür
dc.contributor.author Türkmen, Serdar
dc.date.accessioned 2025-07-22T11:48:06Z
dc.date.available 2025-07-22T11:48:06Z
dc.date.issued 2020
dc.identifier.issn 2148-4902
dc.identifier.uri http://dspace.adiyaman.edu.tr:8080/xmlui/handle/20.500.12414/6480
dc.description.abstract Endothelial cell dysfunction proceeding with increased inflammation and monocyte increase is one of the main causes of vessel injury in CAD. SIRT1 (Sirtuin 1) protein plays an important role in the regulation of cellular physiological mechanisms. SIRT1 has roles in regulating angiogenesis and preventing endothelial dysfunction and reperfusion injury due to ischemia. Suppression of SIRT1 causes monocyte affinity due to endothelial dysfunction. Sirtuins activators are involved in pathologies of many diseases with promising treatments. The objective of this review is to summarize the current progress and future directions of sirtuin protein in the field of CAD. tr
dc.language.iso en tr
dc.publisher KARE PUBL tr
dc.subject Coronary artery disease tr
dc.subject endothelial cell dysfunction tr
dc.subject inflammation tr
dc.subject Sirtuin 1 tr
dc.title The relationship between coronary artery disease and SIRT1 protein tr
dc.type Other tr
dc.contributor.authorID 0000-0001-7768-2562 tr
dc.contributor.authorID 0000-0002-0598-7284 tr
dc.contributor.authorID 0000-0002-4120-4275 tr
dc.contributor.department Adiyaman Training & Res Hosp, Dept Cardiol, tr
dc.identifier.endpage 635 tr
dc.identifier.issue 6 tr
dc.identifier.startpage 631 tr
dc.identifier.volume 7 tr
dc.source.title NORTHERN CLINICS OF ISTANBUL tr


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