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Gastroesophageal reflux disease is associated with abnormal ventricular repolarization indices

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dc.contributor.author Kaya, Hakan
dc.contributor.author Barutcu, Sezgin
dc.date.accessioned 2025-02-17T10:40:05Z
dc.date.available 2025-02-17T10:40:05Z
dc.date.issued 2019
dc.identifier.issn 2148-5607
dc.identifier.uri http://dspace.adiyaman.edu.tr:8080/xmlui/handle/20.500.12414/5803
dc.description.abstract Background/Aims: Gastroesophageal Reflux Disease (GERD) is a clinical entity affecting the upper gastrointestinal tract. The pathophysiology of GERD has been associated with autonomic nervous system disorders. Autonomic nervous system disturbances in GERD patients have been shown to lead to fatal ventricular arrhythmias (VAs) that result in electrical and ventricular repolarization anomalies. The maximum to terminal electrocardiographic T wave (Tpe) has been associated with repolarization of transmural dispersion. In addition, a higher Tpe interval (TpeI) and Tpe/QT ratio correspond with VAs. The goal of this report was to assess ventricular repolarization, by TpeI and Tpe/QT ratio, in GERD patients. Materials and Methods: The study was comprised of 46 GERD subjects and 43 healthy volunteers. TpeI, cTpe, and Tpe/Q ratios were determined from electrocardiograms and associations of the groups were compared. Results: The clinical characteristics were similar between the two groups. Tpel, corrected Tpe (cTpe) interval, and Tpe/QT ratio were higher in subjects with GERD in comparison to the control group (P<0.001, P=0.018, and P<0.001, respectively). Conclusion: TpeI and Tpe/QT ratio were higher in GERD patients. Patients with GERD may have an increased risk for VAs tr
dc.language.iso en tr
dc.publisher AVES tr
dc.subject Gastroesophageal reflux tr
dc.subject Tpe interval tr
dc.subject Tpe/QT ratio tr
dc.subject ventricular arrhythmia tr
dc.title Gastroesophageal reflux disease is associated with abnormal ventricular repolarization indices tr
dc.type Article tr
dc.contributor.authorID 0000-0003-0823-3215 tr
dc.contributor.department Adiyaman Univ, Dept Cardiol, tr
dc.contributor.department Adiyaman Training & Res Hosp, Dept Gastroenterol, tr
dc.identifier.endpage 1024 tr
dc.identifier.issue 12 tr
dc.identifier.startpage 1021 tr
dc.identifier.volume 30 tr
dc.source.title TURKISH JOURNAL OF GASTROENTEROLOGY tr


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