Outcome of UVA-Riboflavin collagen cross-linking of cornea in patients with keratoconus

Abstract

Purpose: In this study, we aimed to show changes of central corneal thickness and effects of treatment on visual acuity after corneal collagen cross-linking in keratoconus patients.

Materials and Methods: 26 eyes of 51 patients with keratoconus who undergone corneal collagen cross-linking were included in to the study. Central corneal thickness measurements and best corrected visual acuity were recorded before and after 1st and 6th month of corneal collagen cross-linking operation.

Results: Mean central corneal thickness measurements were recorded as; 435,43 +/- 44,35 mu m, 376,68 +/- 66,55 mu m and 392,62 +/- 64,21 mu m before and after 1st and 6th month of corneal collagen cross-linking, respectively. There was a statistically significant difference between pre-op and postop 1st month, pre-op and postop 6th month and postop 1st month and post-op 6th month central corneal thickness measurements. Also, there was a statistically significant increase in best corrected visual acuity after the operation.

Conclusion: There was a statistically significant difference between pre-op, post-op 1st month and postop 6th month central corneal thickness and best corrected visual acuity measurements.