Changes In Mpv, Pct And Other Laboratory Parameters In Children With Adenovirus Gastroenteritis

Abstract

Aim: Enteric adenoviruses are the second most common cause of acute and prolonged diarrhea due to viral gastroenteritis a er rotaviruses. Mean platelet volume ( MP) is a marker of platelet function and activation. MP can increase or decrease based on the severity of systemic inflammation in various inflammatory and infectious conditions. The aim of this study was to evaluate the changes in some platelet indices and other laboratory parameters in children with adenovirus gastroenteritis. Material and Method: A total of 61 patients aged under 5 years who were diagnosed with acute adenovirus gastroenteritis in the county healthcare facilities affliated with the Adiyaman General Secretariat of Public Hospitals between January 2014 and December 2016 and clinically followed-up at the clinic were included in the study together with 64 healthy control subjects. Results: The 61 patients with adenovirus gastroenteritis consisted of 29 females and 32 males with a mean age of 23.70 +/- 18.8 (2-60) months. The 64 healthy children in the control group consisted of 29 females and 35 males with a mean age of 24.87 +/- 14.81 (1-54) months. We found a significant and highly positive correlation between PCT and PLT,WBC,HGB, AST were found to have potential value for the differential diagnosis. We also found that PCT and MPV had no diagnostic value in the diffrential diagnosis of adenovirus gastroenteritis. Discussion: The MP value was significantly lower in the adenovirus gastroenteritis patients than the control group. We therefore believe that MPV could be used as a negative acute phase reactant in adenovirus gastroenteritis.