Microwave Assisted Suzuki-Miyaura and Ullmann Type Homocoupling Reactions of 2-and 3-Halopyridines Using a Pd(OAc)(2)/Benzimidazolium Salt and Base Catalyst System

Abstract

A number of novel benzimidazole derivatives 1-4 were synthesized and the catalytic activity of these compounds in a catalytic system consisting of a benzimidazolium salt/Pd(OAc)(2)/K2CO3 were investigated in the Suzuki-Miyaura and Ullmann type homocoupling reactions under microwave irradiation. We obtained both cross coupling and homocoupling products of pyridine and some side products such as dimethylaminopyridine and unsubstituted pyridine.