ESR study of some gamma irradiated amino acids and condensed 1,4-dihydropyridines

Abstract

L-alanine methyl ester hydrochloride, 2-aminoisobutyric acid and some condensed 1,4-dihydropyridine derivatives (Compounds R1-R4) were gamma irradiated, the induced free radicals was investigated at room temperature by electron spin resonance techniques. The observed paramagnetic species of amino acids compounds were attributed to the CH3<(C)over dot>HCOOCH3 and (CH3)(2)<(C)over dot>COOH radicals, respectively. The observed spectra of the 1,4-dihydropyridine derivatives interpreted in terms of some type of amine radical fragments. The spectra were computer simulated and the g values of the radicals and the hyperfine structure constants of the unpaired electron with nearby protons and N-14 nucleus were determined. In this study, the observed paramagnetic species were found to be stable at room temperature more than 2 months. Published by Elsevier B.V.