Abstract:
Objective: To investigate the effects of CRT (cathode ray tube)-monitor-emitted radiation on the oxidant/antioxidant status in kidney, liver, heart, brain tissues of rats and to observe the histo pathological findings of these tissues, and to examine any protective role of vitamin C supplementation.
Material and Method: The study carried out on 40 Wistar albino adult female rats. There were 10 animals in each four group (control, vitamin C, computer; and computer plus vitamin C). The computer and computer plus vitamin C groups were exposed to computer monitors while the other groups were not. Vitamin C was administered 250 mg/kg/day orally. In the kidney, liver, heart, and brain tissues, malondialdehyde (MDA) levels and superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) activities were measured spectrophotometrically. In addition, histopathological examination is carried out.
Results: In the kidney tissues, MDA levels significantly increased in the computer group compared with the computer plus vitamin C group and the control group (p<0.05). Histomorphologic changes were observed in the kidney and liver tissues of the computer group while there were no alterations in other tissues.
Conclusion: The results of this study suggest that CRT-monitor-emitted radiation leads to oxidative stress and cellular changes in kidney and liver tissues and the antioxidant supplementation like vitamin C could prevent these possible oxidative effects.
