Synthesis, characterization and microwave-assisted catalytic activity of novel benzimidazole salts bearing piperidine and morpholine moieties in Heck cross-coupling reactions

Abstract

A mixture of novel benzimidazole salts (2a-f), Pd(OAc)(2) and K(2)CO(3) in DMF-H(2)O catalyzes, in high yield, the Heck cross-coupling reaction assisted by microwave irradiation in a short time. All synthesized novel benzimidazole derivatives were characterized by elemental analysis and NMR spectroscopy. In addition, the molecular structure of 2a was determined by X-ray crystallography. Copyright (C) 2011 John Wiley & Sons, Ltd.