Adıyaman Üniversitesi Kurumsal Arşivi

Is there a relationship between Toxoplasma gondii infection and idiopathic Parkinson's disease?

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dc.contributor.author Tuncay, Çelik
dc.contributor.author Kamışlı, Özden
dc.contributor.author Babur, Cahit
dc.contributor.author ve diğerleri...
dc.date.accessioned 2022-04-12T10:27:59Z
dc.date.available 2022-04-12T10:27:59Z
dc.date.issued 2010
dc.identifier.issn 0036-5548
dc.identifier.uri http://dspace.adiyaman.edu.tr:8080/xmlui/handle/20.500.12414/2787
dc.description.abstract Idiopathic Parkinson's disease defines a group of Parkinson's disease (PD) of which the aetiology is unknown but an underlying brain disease is suspected. We selected patients of this subgroup of PD and investigated the seropositivity rate for anti-Toxoplasma IgG antibody by Sabin-Feldman dye test (SFDT). By measuring seropositivity in PD patients, we searched for a probable relationship between Toxoplasma gondii infection and idiopathic PD incidence. Fifty patients diagnosed with idiopathic PD and 50 healthy volunteers were included in the study. Blood samples were taken from all 100 participants and anti-T. gondii antibody titres were investigated using SFDT. Anti-T. gondii antibodies were detected at a titre of >= 1/16 in 25 of the 50 patients (50%) and in 20 of the control group (40%). No higher antibody titre was found in the control group. In conclusion, despite the emerging literature on a possible relationship between T. gondii infection and neurological disease, and the high anti-T. gondii seropositivity found in our PD patients, we did not detect any statistically significant association between T. gondii and idiopathic PD. tr
dc.language.iso en tr
dc.publisher Informa Healthcare tr
dc.subject Behavior tr
dc.subject Personalıty tr
dc.subject Mıce tr
dc.subject Orıgın tr
dc.subject Host tr
dc.title Is there a relationship between Toxoplasma gondii infection and idiopathic Parkinson's disease? tr
dc.type Article tr
dc.contributor.authorID 0000-0002-2197-0079 tr
dc.contributor.authorID 0000-0003-1114-7860 tr
dc.contributor.department Adiyaman Univ, Sch Hlth, tr
dc.contributor.department Inonu Univ, Fac Med, Dept Neuro tr
dc.contributor.department Refik Saydam Natl Hyg Ctr, Parasitol Lab, Dept Communicable Dis tr
dc.identifier.endpage 608 tr
dc.identifier.issue 8 tr
dc.identifier.startpage 604 tr
dc.identifier.volume 42 tr
dc.source.title Scandınavıan Journal Of Infectıous Dıseases tr


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