Adıyaman Üniversitesi Kurumsal Arşivi

Synthesis and Antimicrobial Activity of Dinaphtho[2,1-b]furan-2-yl-methanone and Their Oxime Derivatives

Basit öğe kaydını göster

dc.contributor.author Kırılmış, Cumhur
dc.contributor.author Koca, Murat
dc.contributor.author Servi, Süleyman
dc.contributor.author Gür, Seher
dc.date.accessioned 2022-03-22T08:22:38Z
dc.date.available 2022-03-22T08:22:38Z
dc.date.issued 2009
dc.identifier.issn 1300-0527
dc.identifier.uri http://dspace.adiyaman.edu.tr:8080/xmlui/handle/20.500.12414/2592
dc.description.abstract The reaction of 2-hydroxy-1-naphthaldehyde with 1,3-dichloroacetone and potassium carbonate was used to prepare dinaphtho[2,1-b]furan-2-yl-methanone (1) as starting reagents. In order to obtain dinaphtho[2,1-b]furan-2-yl-methanole (2), compound 1 was reduced with NaBH4. N-oxime derivative of this compound (3) was synthesized by the reaction of the compound 1 with hydroxylamine. Alkyl and acyl substituted N-oxime ethers (4-11) were obtained by the reaction compound 3 with various halogen containing compounds. Compound 12 was obtained by reflux of the compound 11 with hydrazine monohydrate in ethanol. Compound 13 was synthesized by the reaction of the compound 11 with NaOH. The synthesized compounds were tested for antimicrobial activity against Salmonella typhimurium, Escherichia coli, Bacillus subtilis, Candida globrata, and Candida tropicalis. All of the selected compounds showed weak antimicrobial activity against test microorganisms (128-512 mu g/mL). tr
dc.language.iso en tr
dc.publisher Scientific Technical Research Council Turkey-TÜBİTAK tr
dc.subject Antimicrobial activity tr
dc.subject Naphtho[2,1-b]furan tr
dc.subject Benzofuran tr
dc.subject Ketoxime tr
dc.title Synthesis and Antimicrobial Activity of Dinaphtho[2,1-b]furan-2-yl-methanone and Their Oxime Derivatives tr
dc.type Article tr
dc.contributor.authorID 0000-0002-9190-4800 tr
dc.contributor.authorID 0000-0002-9250-0293 tr
dc.contributor.authorID 0000-0003-0827-8624 tr
dc.contributor.authorID 0000-0003-0081-5990 tr
dc.contributor.department Adıyaman Üniversitesi/Fen Edebiyat Fakültesi/Kimya Bölümü tr
dc.contributor.department Fırat Üniversitesi/Fen Fakültesi/Kimya Bölümü tr
dc.contributor.department Fırat Üniversitesi/Fen Fakültesi/Biyoloji Bölümü tr
dc.identifier.endpage 384 tr
dc.identifier.issue 3 tr
dc.identifier.startpage 375 tr
dc.identifier.volume 33 tr
dc.source.title Turkish Journal of Chemistry tr


Bu öğenin dosyaları:

Bu öğe aşağıdaki koleksiyon(lar)da görünmektedir.

Basit öğe kaydını göster